Philadelphia Eagles vs Tennessee Titans Prediction, Preview and Odds - 09/20/2026

Game Time: 1:00 pm ET, Sunday, September 20, 2026

Venue:  Nissan Stadium, Nashville, TN

Where to Watch:  FOX

DraftKings:  Point Spread:  Eagles -7, Titans +7; Over/Under:  39.5 points

Bet365:  Point Spread:  Eagles -7, Titans +7; Over/Under:  39.5 points

BetMGM:  Point Spread:  Eagles -7, Titans +7; Over/Under:  39.5 points

Philadelphia Eagles:  1-0 (1st place, NFC East)

Tennessee Titans:  0-1 (2nd place, AFC South)

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Philadelphia Eagles:  won their last game at home against the Washington Commanders 24-22.

Tennessee Titans:  lost their last game at home against the New York Jets 23-10.

The Eagles are entering this game with a 1-0 record overall and they have a 1-0 record in their divisional games too. They are 1-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Washington Commanders 24-22. Jalen Hurts was the starting QB and he completed 14/25 passes for 203 passing yards, 3 touchdowns, and 0 interceptions. Saquon Barkley led the team in rushing yards with 83. Dallas Goedert led the receivers with 77 receiving yards on 4 receptions and 2 TDs. Zack Baun led the defense in that game with 12 solo tackles while Jihaad Campbell led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

The Titans are entering this game with a 0-1 record overall and they have a 0-0 record in their divisional games too. They are 0-1 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the New York Jets 23-10. Cameron Ward was the starting QB and he completed 19/32 passes for 140 passing yards, 1 touchdown, and 0 interceptions. Tony Pollard led the team in rushing yards with 35. Wan'Dale Robinson led the receivers with 38 receiving yards on 5 receptions. Anthony Hill Jr. led the defense in that game with 16 solo tackles while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.

The current betting odds have the Eagles listed as a 7 point favorite in this game according to Draftkings Sportsbook. The Eagles have looked good in their games this season with their 1-0 record overall so far. They haven't played any road games yet and will be playing their 1st road game of the season here. Meanwhile, the Titans have looked terrible in their games this season with their 0-1 record overall so far. They haven't looked great on their home field either with their 0-1 home record this season. The Titans were one of the worst teams in the NFL last season and they look like they are going to be one of the worst teams once again. They had one of the easiest games they could have had to start the season, playing the Jets at home, but they fell flat on their face in Saleh's debut with the team. They lost to the Jets 23-10 and the game was a lot worse than the score suggests as they were never really in that game with a chance to win. The defense wasn't terrible, but it still wasn't great either, and the offense was a big issue with Ward having a lot of trouble in the passing game. Now they have one of the best franchises in the NFL over the last few years coming into town and they are coming off a solid performance. The Eagles beat the Commanders 24-22 and even though the Commanders had a chance to tie the game at the end, the Eagles were still in control for most of the game. The offense still didn't look great, but this is a great opportunity for them to iron out the kinks against this bad Titans defense. The Eagles defense also looked just as good as ever, so this terrible Titans offense that doesn't have a lot of talent is going to have a lot of trouble trying to put up points here. The Eagles still won last week, but they have a lot more talent than this Titans team and they will use this game as a get right game on offense. The best way to place a bet here is on the Eagles to cover the spread in this game. 

Eagles Titans Prediction:  Our NFL Pick for Sunday, September 20, 2026 (1:00 pm ET start time) is Eagles 35 Titans 10.

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Philadelphia Eagles: 12-5 ATS in road games. 9-0 ATS off a win against a division rival. 13-6 ATS after playing a game at home. 18-6 OVER against AFC South division opponents. 

Tennessee Titans: 9-26 ATS in all games. 9-21 ATS as an underdog. 4-14 ATS in home games. 3-11 ATS in a home game where the total is between 35.5 and 42 points. 12-1 OVER after scoring 14 points or less last game.

Philadelphia Eagles:  J. Greenard (LB) Out - Pectoral. E. Stowers (TE) Questionable - Hamstring.

Tennessee Titans:  C. Gray (LB) Out - Concussion. K. Faulk (DL) Injured - Shoulder.

“I think one of the things that makes Jalen such a special quarterback is that he can do it through the air. He can do it running the show. He can do it with his legs when he needs to make plays, and obviously, that was a big play, and you need those.” - Nick Sirianni after his team’s win against the Commanders in their last game. 

“They got after us.” - Robert Saleh after his team’s loss against the Jets in their last game. 

WR Wicks, Dontayvion

WR Smith, DeVonta

WR Lemon, Makai

TE Goedert, Dallas

QB Hurts, Jalen

RB Barkley, Saquon 

WR Ridley, Calvin

WR Tate, Carnell

WR Robinson, Wan'Dale

TE Helm, Gunnar

QB Ward, Cam

RB Pollard, Tony

Passing: Jalen Hurts (203)

Rushing: Saquon Barkley (83)

Receiving: Dallas Goedert (77)

Touchdowns: Dallas Goedert (2)

Passing: Cam Ward (140)

Rushing: Tony Pollard (35)

Receiving: Carnell Tate (38)

Touchdowns: Elic Ayomanor (1)

Coaches:

Philadelphia Eagles: Nick Sirianni (6th season)

Tennessee Titans: Robert Saleh (1st season)