New York Giants vs Houston Texans Prediction, Preview and Odds - 10/25/2026

Game Time: 1:00 pm ET, Sunday, October 25, 2026

Venue:  Reliant Stadium, Houston, TX 

Where to Watch:  FOX

DraftKings:  Point Spread:  Giants +10.5, Texans -10.5; Over/Under:  42.5 points

Bet365:  Point Spread:  Giants +10.5, Texans -10.5; Over/Under:  42.5 points

BetMGM:  Point Spread:  Giants +10.5, Texans -10.5; Over/Under:  42.5 points

New York Giants:  3-2-1 (1st place, NFC East)

Houston Texans:  2-4 (3rd place, AFC South)

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New York Giants:  lost their last game at home against the New Orleans Saints 34-27.

Houston Texans:  won their last game at a neutral site against the Jacksonville Jaguars 34-31.

The Giants are entering this game with a 3-2-1 record overall and they have a 1-0-1 record in their divisional games too. They are 3-1 in their home games, 0-1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the New Orleans Saints 34-27. Jameis Winston was the starting QB and he completed 14/26 passes for 152 passing yards, 1 touchdown, and 2 interceptions before getting replaced by J.J. McCarthy who completed 11/21 passes for 243 yards, 1 TD, and 1 INT. J.J. McCarthy led the team in rushing yards with 26. Malik Nabers led the receivers with 165 receiving yards on 12 receptions. Tremaine Edmunds and Jevon Holland each led the defense in that game with 9 solo tackles while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.

 

 

 

The Texans are entering this game with a 2-4 record overall and they have a 2-1 record in their divisional games too. They are 0-3 in their home games, 1-1 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Jacksonville Jaguars 34-31. C. J. Stroud was the starting QB and he completed 24/34 passes for 312 passing yards, 3 touchdowns, and 1 interception. Jo'quavious Marks led the team in rushing yards with 56. Jaylin Noel led the receivers with 107 receiving yards on 4 receptions and 1 TD. Kamari Lassiter led the defense in that game with 8 solo tackles while no one on the defense recorded a sack for them. Calen Bullock came away with the only interception for them in that one.

The current betting odds have the Giants listed as a 10.5 point underdog in this game according to Draftkings Sportsbook. The Giants have looked good in their games this season with their 3-2-1 record overall which has them right at the top of the NFC East. They haven't been a great road team though with their 0-1-1 road record this year. Meanwhile, the Texans haven't looked great in their games this season with their 2-4 record overall which has them right in the middle of the AFC South. They have looked terrible on their home field too with their 0-3 home record this season. The Texans have won 2 games in a row now and their offense has been rolling in these games, but this is still a team that started the season 0-4. They have been working their way back from that hole and they are coming off a 34-31 win over the Jaguars in London, but their defense hasn't looked great this season. They had one of the best defenses in the NFL last season, but this year they have been giving up a ton of points. This isn't a great situation for the Texans either, coming off a big divisional win in London and then coming back without taking their bye week. The Giants have been a good team this season and it looks like Harbaugh has them on the right track. It looked like the season was over when Dart got injured, but they have managed to stay afloat and still lead a bad division. They are coming off a 34-27 loss to the Saints in their last one and they were down so much before starting to come back late, but a lot of that was McCarthy coming in for Winston and now he is going to get the start in this game which could give the Giants offense some life here. This is a bad situation for the Texans and that defense hasn't looked nearly as good as last season, so look for the Giants to keep this a closer game. The best way to place a bet here is on the Giants to cover the spread in this game. 

Giants Texans Prediction:  Our NFL Pick for Sunday, October 25, 2026 (1:00 pm ET start time) is Texans 24 Giants 17.

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New York Giants: 6-13 ATS in all games where the total is between 42.5 and 49 points. 2-8 ATS after allowing 30 points or more last game. 4-8 ATS vs. good passing teams averaging 235 or more passing yards/game. 20-11 UNDER off 3 or more consecutive overs. 30-19 UNDER versus good rushing defenses - allowing 3.5 rushing yards/carry or less. 

Houston Texans: 9-3 ATS after playing a division game. 7-3 ATS after a win by 6 or less points. 8-2 ATS off a win against a division rival. 8-3 ATS when playing against a good team (Win Pct. 60% to 75%). 17-4 UNDER in all games where the total is between 42.5 and 49 points. 9-2 UNDER after a win by 6 or less points.

New York Giants:  C. Manhertz (TE) Injured - Calf. J. Eluemunor (OG) Injured - Calf. T. Edmunds (LB) Injured - Shoulder. C. Jones (WR) Injured - Achilles. A. Thomas (OT) Injured - Groin. P. Adebo (CB) Injured - Knee. D. Mooney (WR) Injured - Neck. G. Newsome II (CB) Injured - Concussion. J. Holland (S) Injured - Concussion. K. Thibodeaux (LB) Injured - Illness. J. Stout (P) Injured - Knee. T. Johnson (TE) Injured - Neck. T. Nubin (S) Injured - Neck. T. Fidone II (TE) Injured - Shoulder. M. Mbow (OG) Injured - Knee. C. Hood (CB) Injured - Concussion.

Houston Texans:  B. Jordan (TE) Injured - Foot. E. Ingram (OG) Injured - Back. A. Al-Shaair (LB) Injured - Knee. T. Dell (WR) Injured - Knee. J. Pitre (S) Injured - Shoulder. R. Blankenship (S) Injured - Concussion. D. Montgomery (RB) Injured - Groin. H. To'oTo'o (LB) Injured - Shoulder. B. Fisher (OT) Injured - Thumb. T. Brown (OT) Injured - Wrist. D. Schultz (TE) Injured - Quad. J. Clowney (DL) Injured - Knee. L. Hall (DL) Injured - Knee.

“I myself, personally, just left a lot of plays out there that I could have executed better on. (McCarthy) was able to rally us up, and he did a great job. I was proud of him. Proud of what he did.” - Jameis Winston after their loss against the Saints in their last game. 

“His mindset was 'Hey, I got you Coach, don’t worry about it. When a player tells me that, that just gives me the confidence that I need. He responded in an outstanding way.” - DeMeco Ryans on C.J. Stroud after his team’s win against the Jaguars in their last game. 

WR Nabers, Malik

WR Fields, Malachi

WR Mooney, Darnell

TE Likely, Isaiah

QB McCarthy, J.J.

RB Skattebo, Cam

FB Ricard, Patrick

WR Collins, Nico

WR Harrison Jr., Marvin

WR Noel, Jaylin

TE Schultz, Dalton

QB Stroud, C.J.

RB Marks, Woody

Passing: Jameis Winston (957)

Rushing: Cam Skattebo (294)

Receiving: Malik Nabers (494)

Touchdowns: Isaiah Likely (5)

Passing: C.J. Stroud (1,714)

Rushing: Woody Marks (205)

Receiving: Jaylin Noel (334)

Touchdowns: David Montgomery (3)

Coaches:

New York Giants: John Harbaugh (1st season)

Houston Texans: DeMeco Ryans (4th season)