Game Time: 4:05 pm ET, Sunday, November 1, 2026
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Chargers +6.5, Rams -6.5; Over/Under: 45.5 points
Bet365: Point Spread: Chargers +6.5, Rams -6.5; Over/Under: 45 points
BetMGM: Point Spread: Chargers +6.5, Rams -6.5; Over/Under: 45 points
Season Record
Los Angeles Chargers: 0-6 (4th place, AFC West)
Los Angeles Rams: 3-4 (3rd place, NFC West)
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Los Angeles Chargers: lost their last game on the road against the Kansas City Chiefs 22-6.
Los Angeles Rams: won their last game on the road against the Las Vegas Raiders 35-21.
Los Angeles Chargers vs Los Angeles Rams Preview and Analysis
The Chargers are entering this game with a 0-6 record overall and they have a 0-3 record in their divisional games too. They are 0-3 in their home games, 0-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Kansas City Chiefs 22-6. Justin Herbert was the starting QB and he completed 22/37 passes for 204 passing yards, 0 touchdowns, and 1 interception. Justin Herbert led the team in rushing yards with 26. Quentin Johnston led the receivers with 57 receiving yards on 1 reception. Tarheeb Still led the defense in that game with 8 solo tackles while no one on the defense recorded a sack for them. Cam Hart came away with the only interception for them in that one.
The Rams are entering this game with a 3-4 record overall and they have a 0-2 record in their divisional games too. They are 1-2 in their home games, 2-1 in their road games, and they are also 0-1 in their neutral site games this season, but they will be at home for this game. They won their last game against the Las Vegas Raiders 35-21. Matthew Stafford was the starting QB and he completed 23/29 passes for 195 passing yards, 3 touchdowns, and 1 interception. Kyren Williams led the team in rushing yards with 99 and 1 TD. Puka Nacua led the receivers with 68 receiving yards on 8 receptions and 1 TD. Quentin Lake led the defense in that game with 7 solo tackles while Byron Young and Braden Fiske each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Chargers vs Rams Prediction
The current betting odds have the Rams listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The Rams haven't looked great in their games this season with their 3-4 record overall which has them right near the bottom of the NFC West. They haven't looked great on their home field either with their 1-2 home record this season. Meanwhile, the Chargers have looked terrible in their games this season with their 0-6 record overall which has them right at the bottom of the AFC West. They haven't been a good road team either with their 0-3 road record this year. The Chargers are coming off a 22-6 loss to the Chiefs in their last one and now they are coming out of their bye week, but they have been a complete disaster all season. Their defense hasn't been terrible, but their offense has been and it doesn't help that they are dealing with a ton of injuries. They are the only team left in the NFL this season that hasn't won a game yet and it doesn't look like it is going to get any better for them with the teams coming up on their schedule. The Rams haven't looked that great themselves this season, being the Super Bowl favorites at the start of the year, but they looked a lot better in their last one and could be turning the corner now. They took a really bad loss to the Cardinals 18-16 just 2 weeks ago, but that loss really gave them a wake-up call and they answered it with a 35-21 win over the Raiders in their last one. Their defense hasn't looked that great this season, but they still have a ton of talent to work with. They also have a lot more talent on offense and they aren't nearly as banged up as the Chargers who look like they have no light at the end of the tunnel. Look for the Rams to take advantage of a Chargers team that has been a disaster all season and use this as a get right game to get back to .500. The best way to place a bet here is on the Rams to cover the spread in this game.
Chargers Rams Prediction: Our NFL Pick for Sunday, November 1, 2026 (4:05 pm ET start time) is Rams 27 Chargers 17.
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NFL Betting Trends
Los Angeles Chargers: 1-4 ATS off a loss against a division rival. 2-6 ATS versus good rushing teams - averaging 4.5 rushing yards/carry or more. 7-1 UNDER as an underdog of 3.5 to 9.5 points. 8-3 UNDER in a road game where the total is between 42.5 and 49 points. 9-5 UNDER after playing a division game.
Los Angeles Rams: 9-4 ATS in non-conference games. 43-32 ATS when playing against a terrible team (Win Pct. <=25%). 28-19 ATS at home after a win by 14 or more points. 8-2 UNDER as a home favorite of 7 points or less. 5-1 UNDER vs. poor passing defenses - allowing 7 or more passing yards/att.
Key Injuries
Los Angeles Chargers: K. Mack (LB) Injured - Rest. D. James Jr. (S) Injured - Hamstring. D. Jackson (CB) Injured - Hamstring. K. Awosika (OG) Injured - Fibula. D. Leonard (CB) Injured - Concussion. L. McConkey (WR) Injured - Concussion. T. Harris (WR) Injured - Hamstring. B. Thompson (WR) Injured - Quad. R. Shelley (CB) Injured - Hamstring.
Los Angeles Rams: J. Cardona (LS) Injured - Ankle. C. Shelton (OG) Injured - Hip. N. Landman (LB) Injured - Concussion. C. Parkinson (TE) Injured - Rib. D. Johnson (LB) Injured - Hip. T. McDuffie (CB) Injured - Groin.
Notable Quotes
“There's no justification. There's nothing I would say that wouldn't sound like an excuse. I'm opposed to that to the core, and pointing fingers. But I believe this is a team game. Definitely, offensively, we need to evaluate. We need to look at it all — everything we're doing, how we're doing it.” - Jim Harbaugh after his team’s loss against the Chiefs in their last game.
“This league is so humbling. Humility is only a day away, but I was proud of the way the group prepared and, most importantly, celebrating each other’s success, having the right energy when you’re on the road and it’s just you versus the opponent and their fans.” - Sean McVay after his team’s win against the Raiders in their last game.
Starting Lineups
Los Angeles Chargers
WR Johnston, Quentin
WR Harris, Tre'
WR McConkey, Ladd
TE Kolar, Charlie
QB Herbert, Justin
RB Hampton, Omarion
FB Matlock, Scott
Los Angeles Rams
WR Whittington, Jordan
WR Nacua, Puka
WR Mumpfield, Konata
TE Higbee, Tyler
QB Stafford, Matthew
RB Williams, Kyren
Statistical Leaders
Los Angeles Chargers
Passing: Justin Herbert (1,141)
Rushing: Omarion Hampton (289)
Receiving: Tre' Harris (225)
Touchdowns: Omarion Hampton (3)
Los Angeles Rams
Passing: Matthew Stafford (1,989)
Rushing: Kyren Williams (492)
Receiving: Puka Nacua (485)
Touchdowns: Kyren Williams (6)
Coaches:
Los Angeles Chargers: Jim Harbaugh (3rd season)
Los Angeles Rams: Sean McVay (10th season)