Kansas City Chiefs vs Denver Broncos Prediction, Preview and Odds - 11/01/2026

Game Time: 4:25 pm ET, Sunday, November 1, 2026

Venue:  Empower Field at Mile High, Denver, CO 

Where to Watch:  CBS

DraftKings:  Point Spread:  Chiefs -1.5, Broncos +1.5; Over/Under:  40.5 points

Bet365:  Point Spread:  Chiefs -1.5, Broncos +1.5; Over/Under:  40.5 points

BetMGM:  Point Spread:  Chiefs -1.5, Broncos +1.5; Over/Under:  40.5 points

Kansas City Chiefs:  5-1 (1st place, AFC West)

Denver Broncos:  5-2 (2nd place, AFC West)

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Kansas City Chiefs:  lost their last game on the road against the Seattle Seahawks 20-3.

Denver Broncos:  won their last game on the road against the Arizona Cardinals 30-16.

The Chiefs are entering this game with a 5-1 record overall and they have a 3-0 record in their divisional games too. They are 3-0 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Seattle Seahawks 20-3. Patrick Mahomes was the starting QB and he completed 19/33 passes for 165 passing yards, 0 touchdowns, and 1 interception. Kenneth Walker III led the team in rushing yards with 36. Travis Kelce led the receivers with 44 receiving yards on 4 receptions. Drue Tranquill led the defense in that game with 12 solo tackles while no one on the defense recorded a sack for them. Nohl Williams came away with the only interception for them in that one.

 

 

 

The Broncos are entering this game with a 5-2 record overall and they have a 1-1 record in their divisional games too. They are 3-0 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Arizona Cardinals 30-16. Bo Nix was the starting QB and he completed 15/29 passes for 222 passing yards, 1 touchdown, and 0 interceptions. Bo Nix led the team in rushing yards with 73 and 1 TD. RJ Harvey led the receivers with 54 receiving yards on 2 receptions and 1 TD. Alex Singleton led the defense in that game with 19 solo tackles while Alex Singleton, Malcolm Roach, and Sai'vion Jones each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Broncos listed as a 1.5 point underdog in this game according to Draftkings Sportsbook. The Broncos have looked good in their games this season with their 5-2 record overall which has them right near the top of the AFC West. They have looked great on their home field too with their 3-0 home record this season. Meanwhile, the Chiefs have looked good in their games this season with their 5-1 record overall which has them right at the top of the AFC West. They have been a good road team too with their 2-1 road record this year. The Chiefs are coming off a 20-3 road loss to the Seahawks in their last one and they finally looked human for the 1st time this year. They were rolling right out of the gates this season and their offense has looked a lot better with the addition of Walker. Their defense has also looked good this season, but their offense really got exposed in that embarrassing loss to the Seahawks. They did beat the Broncos 31-10 earlier this year, but that was also the 1st week of the season when teams weren't at their best. The Broncos defense looked terrible in that game and couldn't really tackle, but lately they have looked a lot better and they are starting to look like the defense that was one of the best in the NFL last season. The Broncos are coming off a 30-16 win over the Cardinals in their last one and their offense looked a lot better in that win. Their offense has had trouble all season with Bo Nix struggling a lot, but he looked a lot better against the Cardinals and there is no doubt that the Broncos are going to bring their best effort here after what happened in week 1. The Broncos are still undefeated at home this season too and have looked like a different team there, so look for the Broncos to get their revenge on the Chiefs. The best way to place a bet here is on the Broncos to cover the spread in this game. 

Chiefs Broncos Prediction:  Our NFL Pick for Sunday, November 1, 2026 (4:25 pm ET start time) is Broncos 24 Chiefs 20.

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Kansas City Chiefs: 6-12 ATS in road games. 4-10 ATS versus division opponents. 5-13 ATS when playing against a team with a winning record. 9-3 UNDER as a road favorite of 7 points or less. 11-0 UNDER in all games where the total is between 35.5 and 42 points.

Denver Broncos: 26-18 ATS in all games. 16-6 ATS in home games. 6-1 ATS revenging a road loss against an opponent. 12-5 ATS when playing against a team with a winning record. 13-7 UNDER as an underdog. 7-2 UNDER vs. good teams - outscoring opponents by 6+ PPG on the season.

Kansas City Chiefs:  M. Delane (CB) Injured - Shoulder. L. Sneed (CB) Injured - NIR - Personal. K. Benson (OT) Injured - Ankle. N. Bolton (LB) Injured - Neck. C. Humphrey (C) Injured - Toe. T. Kelce (TE) Injured - Ankle. J. Moore (OG) Injured - Concussion. O. Norman-Lott (DL) Injured - Knee. R. Rice (WR) Injured - Hamstring. D. Tranquill (LB) Injured - Elbow. P. Mahomes (QB) Injured - Knee.

Denver Broncos:  R. Harvey (RB) Injured - Knee. B. Jones (S) Injured - Hamstring. J. Waddle (WR) Injured - Chest. K. Reid (LB) Injured - Elbow. M. Roach (DL) Injured - Neck. P. Surtain II (CB) Injured - Ankle. G. Bolles (OT) Injured - Hip. M. Mims Jr. (WR) Injured - Ankle. Z. Allen (DL) Injured - Hamstring. T. Hufanga (S) Injured - Ankle.

“Listen, all three phases we struggled, so we’ve got to do better, and that’s my responsibility. So I take full responsibility for this. We’ve got to play better as a team.” - Andy Reid after his team’s loss against the Seahawks in their last game. 

“I think it answers our question, ‘Can he can still run?’ The confidence inside the building relative to his abilities hasn't changed at all. He's our guy and it's good to see him play well. It's good to see us block well and make some plays down the field.” - Sean Payton after his team’s win against the Cardinals in their last game. 

WR Royals, Jalen

WR Worthy, Xavier

WR Armstrong, Andrew

TE Kelce, Travis

QB Mahomes, Patrick

RB Walker, Kenneth

FB VanSumeren, Ben

WR Sutton, Courtland

WR Waddle, Jaylen

WR Franklin, Troy

TE Engram, Evan

QB Nix, Bo

RB Dobbins, J.K.

FB Prentice, Adam

Passing: Patrick Mahomes (1,474)

Rushing: Kenneth Walker III (701)

Receiving: Travis Kelce (343)

Touchdowns: Kenneth Walker III (8)

Passing: Bo Nix (1,271)

Rushing: J.K. Dobbins (293)

Receiving: Jaylen Waddle (276)

Touchdowns: J.K. Dobbins (3)

Coaches:

Kansas City Chiefs: Andy Reid (14th season)

Denver Broncos: Sean Payton (4th season)