Denver Broncos vs Kansas City Chiefs Prediction, Preview and Odds - 09/14/2026

Game Time: 8:15 pm ET, Monday, September 14, 2026

Venue:  Arrowhead Stadium, Kansas City, MO

Where to Watch:  ESPN, ABC

DraftKings:  Point Spread:  Broncos +3, Chiefs -3; Over/Under:  42.5 points

Bet365:  Point Spread:  Broncos +2.5, Chiefs -2.5; Over/Under:  43.5 points

BetMGM:  Point Spread:  Broncos +2.5, Chiefs -2.5; Over/Under:  43.5 points

Denver Broncos:  0-0 (AFC West)

Kansas City Chiefs:  0-0 (AFC West)

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Denver Broncos:  N/A

Kansas City Chiefs:  N/A

The Broncos finished last season with a 14-3 record overall and they were 5-1 in their division games too. They had an 8-1 record in their home games and had a 6-2 record in their road games where they will be in this game. Last season, their offense was averaging 23.6 points per game and their defense was allowing an average of 18.3 points per game. Their offense was also averaging 342.6 yards per game and their defense was allowing an average of 278.2 yards per game. Bo Nix led the team in passing yards with 3,931, J.K. Dobbins led the team in rushing yards with 772, and Courtland Sutton led the team in receiving yards with 1,017.

The Chiefs finished last season with a 6-11 record overall and they were 1-5 in their division games too. They had a 5-4 record in their home games and had a 1-7 record in their road games where they will be in this game. Last season, their offense was averaging 21.3 points per game and their defense was allowing an average of 19.3 points per game. Their offense was also averaging 320.6 yards per game and their defense was allowing an average of 301.5 yards per game. Patrick Mahomes led the team in passing yards with 3,587, Kareem Hunt led the team in rushing yards with 611, and Travis Kelce led the team in receiving yards with 851.

The current betting odds have the Chiefs listed as a 3 point favorite in this game according to Draftkings Sportsbook. The Chiefs had a 6-11 record overall last season and the wheels really fell off for them. It was the first time in years that they didn't win the division or even make the playoffs. They were having trouble throughout the year anyway, but the injury to Mahomes really sealed their coffin. Now Mahomes will be back though and he will breathe some life into this offense that looked so bad without him last year. They still have plenty of talent for him to throw the ball to and the team has always had a good defense the last few years, defense being the backbone of the team. Meanwhile, the Broncos had a 14-3 record overall last season and they won the AFC West. They were one of the best teams in the NFL last season with one of the best defenses in the league and they probably get to the Super Bowl if Bo Nix doesn't break his leg before the AFC Championship. They are still going to have one of the best defenses in the NFL this season, but the offense still doesn't have a ton of talent and Bo Nix was also really up and down last season from game to game. As good as the Broncos defense is too, Mahomes is still the much better QB in this matchup and will make more plays when the Chiefs need it most. The Chiefs also have a good enough defense themselves to hold this Broncos offense at bay on the road in this season opener. The best way to place a bet here is on the Chiefs to cover the spread in this game.

Broncos Chiefs Prediction:  Our NFL Pick for Monday, September 14, 2026 (8:15 pm ET start time) is Chiefs 24 Broncos 20.

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Denver Broncos: 5-3 ATS as a road underdog of 7 points or less. 17-10 ATS in games played on a grass field. 11-6 UNDER in all games where the total is between 42.5 and 49 points. 7-4 UNDER as a road underdog.

Kansas City Chiefs: 14-22 ATS in all games. 11-19 ATS as a favorite. 2-9 ATS versus division opponents. 24-13 UNDER in all games. 20-11 UNDER as a favorite.

Denver Broncos:  None.

Kansas City Chiefs:  None.

"We're pleased with what transpired in the last 24 hours, for the most part, as we looked at it." - Sean Payton on his team’s roster coming into this new NFL season.

“I like the way the running backs were running. They were hitting it and seeing it. It looks like they have good vision, which helps you, too. Enough patience, but good vision.” - Andy Reid on his team’s running back room coming into this new season.

WR Sutton, Courtland

WR Waddle, Jaylen

WR Bryant, Pat 

TE Trautman, Adam

QB Nix, Bo

RB Dobbins, J.K.

WR Thornton, Tyquan

WR Worthy, Xavier

WR Rice, Rashee

TE Kelce, Travis

QB Mahomes, Patrick

RB Walker, Kenneth

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Coaches:

Denver Broncos: Sean Payton (4th season)

Kansas City Chiefs: Andy Reid (14th season)