Denver Broncos vs Carolina Panthers Prediction, Preview and Odds - 11/08/2026

Game Time: 1:00 pm ET, Sunday, November 8, 2026

Venue:  Bank of America Stadium, Charlotte, NC

Where to Watch:  CBS

DraftKings:  Point Spread:  Broncos -2.5, Panthers +2.5; Over/Under:  43.5 points

Bet365:  Point Spread:  Broncos -3, Panthers +3; Over/Under:  44 points

BetMGM:  Point Spread:  Broncos -3, Panthers +3; Over/Under:  43.5 points

Denver Broncos:  6-2 (1st place, AFC West)

Carolina Panthers:  3-4 (1st place, NFC South)

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Denver Broncos:  won their last game at home against the Kansas City Chiefs 28-24.

Carolina Panthers:  lost their last game on the road against the Green Bay Packers 27-19.

The Broncos are entering this game with a 6-2 record overall and they have a 2-1 record in their divisional games too. They are 4-0 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Kansas City Chiefs 28-24. Bo Nix was the starting QB and he completed 20/32 passes for 222 passing yards, 2 touchdowns, and 0 interceptions. Jonah Coleman led the team in rushing yards with 41 and 1 TD. Jonah Coleman led the receivers with 63 receiving yards on 4 receptions. Alex Singleton led the defense in that game with 14 solo tackles while Alex Singleton and Malcolm Roach each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

The Panthers are entering this game with a 3-4 record overall and they have a 1-1 record in their divisional games too. They are 1-2 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Green Bay Packers 27-19. Bryce Young was the starting QB and he completed 23/41 passes for 209 passing yards, 1 touchdown, and 1 interception. Chuba Hubbard led the team in rushing yards with 81 and 1 TD. Tetairoa McMillan led the receivers with 58 receiving yards on 6 receptions. Marco Wilson led the defense in that game with 8 solo tackles while no one on the defense recorded a sack for them. Zakee Wheatley came away with the only interception for them in that one.

The current betting odds have the Broncos listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Broncos have looked good in their games this season with their 6-2 record overall which has them right at the top of the AFC West. They haven't been a great road team though with their 2-2 road record this year. Meanwhile, the Panthers haven't looked great in their games this season with their 3-4 record overall, but that record has them right at the top of the NFC South. They haven't looked great on their home field either with their 1-2 home record this season. The Panthers had a nice start to the season, but lately they haven't looked great. They are still leading the NFC South since they are in a weak division, but their grip is starting to loosen and they are coming off a 27-19 loss to the Packers in their last one. They had a great offense to start the year with Bryce Young looking like a franchise QB, but lately the offense has been having a lot of trouble putting up points and their defense has looked terrible all year. The Broncos had a rough start to the season, but they have gotten themselves back on the winning path and they have been doing it with a tougher schedule too. They are coming off a 28-24 win over the Chiefs in their last one and they once again came alive in the 4th quarter, finding a way to win a game that they were trailing in most of the time. Their offense hasn't looked great this season, but Bo Nix is the type of QB that has shown up in big moments and they do have one of the best defenses in the NFL to lean on too. The best way to place a bet here is on the Broncos to cover the spread in this game.

Broncos Panthers Prediction:  Our NFL Pick for Sunday, November 8, 2026 (1:00 pm ET start time) is Broncos 24 Panthers 17.

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Denver Broncos: 24-44 ATS off a home win against a division rival. 3-7 ATS in a road game where the total is between 42.5 and 49 points. 47-66 ATS on the road in games where the line is +3 to -3. 9-5 OVER when playing against a team with a losing record. 12-4 OVER vs. bad defensive teams who give up 24 or more points/game.

Carolina Panthers: 11-6 ATS as a home underdog. 16-10 ATS in all games where the total is between 42.5 and 49 points. 9-4 ATS off a road loss. 13-3 OVER in a home game where the total is between 42.5 and 49 points. 13-6 OVER after playing their last game on the road.

Denver Broncos:  None.

Carolina Panthers:  None.

“Obviously a big win. And I'm proud of the grit.” - Sean Payton after his team’s win against the Chiefs in their last game. 

“Love the fight in the group. Didn’t expect anything less. The guys kept battling all the way through, gave us some opportunities at the end.” - Dave Canales after his team’s loss against the Packers in their last game. 

WR Sutton, Courtland

WR Waddle, Jaylen

WR Franklin, Troy

TE Engram, Evan

QB Nix, Bo

RB Coleman, Jonah

FB Prentice, Adam

WR McMillan, Tetairoa

WR Metchie III, John

WR Coker, Jalen

TE Tremble, Tommy

QB Young, Bryce

RB Hubbard, Chuba

Passing: Bo Nix (1,493)

Rushing: J.K. Dobbins (306)

Receiving: Jaylen Waddle (315)

Touchdowns: J.K. Dobbins (3)

Passing: Bryce Young (1,921)

Rushing: Chuba Hubbard (540)

Receiving: Tetairoa McMillan (569)

Touchdowns: Chuba Hubbard (7)

Coaches:

Denver Broncos: Sean Payton (4th season)

Carolina Panthers: Dave Canales (3rd season)