Cleveland Guardians vs Tampa Bay Rays Prediction, Preview and Odds - 10/13/2026

Game Time: 8:00 pm ET, Tuesday, October 13, 2026

Venue:  Tropicana Field, St. Petersburg, FL 

Where to Watch:  TBS, truTV

DraftKings:  Moneyline odds:  Guardians +113, Rays -137; Over/Under:  6.5 runs

Bet365:  Moneyline odds:  Guardians +115, Rays -135; Over/Under:  6.5 runs

BetMGM:  Moneyline odds:  Guardians +115, Rays -135; Over/Under:  6.5 runs

Cleveland Guardians:  85-77 (1st place, AL Central)

Tampa Bay Rays:  98-64 (1st place, AL East)

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Cleveland Guardians:  6-4 last 10

Tampa Bay Rays:  6-4 last 10

The Guardians are entering this series off a win and won their best of 5-game series against the Chicago White Sox 3-2 in the American League Division Series. They finished the regular season with an 85-77 record overall and had a road record of 44-37. This is the 2nd game of a best 4 out of 7 game series with the Rays on Tuesday for the American League Championship Series. Their offense ranks 26th in the MLB with a .696 OPS. Foster Griffin was their starting pitcher on Monday while Parker Messick is making his start in this game on Tuesday. He is 12-9 with a 2.56 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB start, he allowed 2 ER, 0 HR, and 4 BB with 5 Ks on 2 hits through 2.1 IP against the Chicago White Sox.

The Rays are entering this series off a win and completed the sweep in their best of 5-game series against the New York Yankees 3-0 in the ALDS. They finished the regular season with a 98-64 record overall and had a home record of 55-26. This is the 2nd game of a best 4 out of 7 game series with the Guardians on Tuesday for the ALCS. Their offense ranks 8th in the MLB with a .728 OPS. Drew Rasmussen was their starting pitcher on Monday while Freddy Peralta is making his start in this game on Tuesday. He is 10-11 with a 4.42 ERA this season. His team won their last 7 straight games this season with him making an appearance. In his last MLB start, he allowed 1 earned run, 1 homer, and 1 BB with 3 strikeouts on 3 hits through 4.2 innings played against the New York Yankees.

The current betting odds have the Rays listed as a favorite in this game according to Draftkings Sportsbook. The Rays have looked great in their games this season with their 98-64 record overall which had them right at the top of the AL East. They have looked great in their own ballpark too with their 55-26 home record this season. Meanwhile, the Guardians have looked good in their games this season with their 85-77 record overall which had them right at the top of the AL Central. They have been a good road team too with their 44-37 road record this year. The Guardians are entering this game with a 1-0 series lead after winning game 1 of this series by a score of 7-3. They have been rolling lately with 4 wins in a row now, winning 3 straight games against the White Sox after falling down 2-0 in that series, but the Rays did sweep the Yankees in the last round and will be looking to bounce back so they don't fall into a 2-0 hole. Peralta is on the mound for the Rays in this one and he hasn't looked great this season. He is 10-11 with a 4.42 ERA, but lately he has looked a lot better and the team has been having a ton of success with him. He only gave up 1 earned run in his last start and the team has won 8 games in a row now with him starting. Messick is on the mound for the Guardians in this one and he has looked great this season. He is 12-9 with a 2.56 ERA, but lately he hasn't looked great. He only gave up 2 earned runs in his last start, but he didn't even make it 3 full innings and now the team has lost 2 of their last 3 games with him starting. Look for the Rays to bounce back and even up this series before hitting the road for the next 3 games. The best way to place a bet here is on the Rays to win this game. 

Guardians Rays Prediction:  Our MLB Pick for Tuesday, October 13, 2026 (8:00 pm ET start time) is Rays 3 Guardians 2.

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Cleveland Guardians: 274-230 (+33.9 units) on the moneyline in all games. 133-118 (+32.5 units) on the moneyline in road games. 97-111 (+15.1 units) on the moneyline as an underdog of +100 or higher. 68-48 UNDER vs. teams outscoring opp by 0.5 or more runs/game on the season.

Tampa Bay Rays: 48-47 (-11.3 units) on the moneyline against AL Central opponents. 167-159 (-8.2 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 109-127 (-10.5 units) on the moneyline when playing against a team with a winning record. 35-24 UNDER when playing against a team with a winning record.

Cleveland Guardians:  C. Holderman (RP) Fifteen Day IL - Wrist. R. Hoskins (1B) Ten Day IL - Back.

Tampa Bay Rays:  G. Jax (SP) Day To Day - Back. C. Simpson (LF) Day To Day - Foot. T. Wells (RP) Fifteen Day IL - Forearm. J. Melton (LF) Sixty Day IL - Hamstring. G. Cleavinger (RP) Fifteen Day IL - Forearm. S. McClanahan (SP) Fifteen Day IL - Forearm. J. Heasley (RP) Sixty Day IL - Elbow. G. Lux (LF) Sixty Day IL - Shoulder. R. Pepiot (SP) Sixty Day IL - Hip. E. Uceta (RP) Sixty Day IL - Shoulder.

“These guys are so resilient. They believe they're going to win every night. Anything can happen in the ALCS. I'm really proud of them.” - Stephen Vogt after his team’s win against the White Sox in game 5 of the ALDS on Saturday. 

“The exact same. Let's continue what we're doing.” - Kevin Cash after his team’s win against the Yankees in game 3 of the ALDS on Wednesday.

Steven Kwan (L) LF

José Ramírez (S) 3B

Chase DeLauter (L) RF

Jo Adell (R) DH

Nathaniel Lowe (L) 1B

Travis Bazzana (L) 2B

Patrick Bailey (S) C

Petey Halpin (L) CF

Brayan Rocchio (S) SS

Yandy Díaz (R) DH

Jonathan Aranda (L) 1B

Junior Caminero (R) 3B

Ryan Vilade (R) LF

Victor Mesa Jr. (L) RF

Jonny DeLuca (R) CF

Ben Williamson (R) 2B

Taylor Walls (S) SS

Nick Fortes (R) C

Batting Average:  Chase DeLauter (.287)

Hits:  Steven Kwan (152)

Home Runs:  Angel Martínez (18)

RBI:  Brayan Rocchio (73)

Stolen Bases:  José Ramírez (37)

Wins:  Gavin Williams (14)

Saves:  Cade Smith (41)

ERA:  Cade Smith (1.95)

Batting Average:  Chandler Simpson (.306)

Hits:  Yandy Díaz (180)

Home Runs:  Junior Caminero (42)

RBI:  Junior Caminero (101)

Stolen Bases:  Chandler Simpson (46)

Wins:  Drew Rasmussen (16)

Saves:  Bryan Baker (41)

ERA:  Bryan Baker (1.44)

Managers:

Cleveland Guardians: Stephen Vogt (3rd season)

Tampa Bay Rays: Kevin Cash (12th season)