Cleveland Guardians vs Detroit Tigers Prediction, Preview and Odds - 08/11/2026

Game Time: 6:40 pm ET, Tuesday, August 11, 2026

Venue:  Comerica Park, Detroit, MI

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Guardians +105, Tigers -125; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Guardians +105, Tigers -125; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Guardians +105, Tigers -125; Over/Under:  8.5 runs

Cleveland Guardians:  58-61 (4th place, AL Central)

Detroit Tigers:  58-60 (2nd place, AL Central)

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Cleveland Guardians:  3-7 last 10

Detroit Tigers:  7-3 last 10

The Guardians are entering this series off a loss and lost their 3-game series against the Chicago White Sox 2-1 in their last series. They enter this game with a 58-61 record overall and have a road record of 30-30. This is the series opener of a 3-game series with the Tigers on Tuesday and they have Monday off as a day of rest. Their offense ranks 29th in the MLB with a .682 OPS. Joey Cantillo was their starting pitcher on Sunday while Tanner Bibee is making his start in this game on Tuesday. He is 4-11 with a 3.85 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 3 ER, 3 HR, and 0 BB with 10 SO on 4 hits through 5.2 IP against the New York Mets.

The Tigers are entering this series off a win and won their 3-game series against the San Francisco Giants 2-1 in their last series. They enter this game with a 58-60 record overall and have a home record of 30-27. This is the 1st game of a 3-game series with the Guardians on Tuesday and they have Monday off as a day of rest. Their offense ranks 11th in the MLB with a .729 OPS. Troy Melton was their starting pitcher on Sunday while Drew Anderson is making his start in this game on Tuesday. He is 4-4 with a 4.01 ERA this season. His team lost 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 1 walk with 0 strikeouts on 3 hits through 3.2 innings pitched against the Seattle Mariners.

The current betting odds have the Tigers listed as a slight favorite in this game according to Draftkings Sportsbook. The Tigers haven't looked great in their games this season with their 58-60 record overall, but that record has them right near the top of the AL Central. Meanwhile, the Guardians haven't looked great in their games this season with their 58-61 record overall which has them right near the bottom of the AL Central. They haven't been a great road team either with their 30-30 road record this year. The Guardians are coming off a series loss to the White Sox and they have looked terrible lately, now 3-7 in their last 10 games and sliding down the standings. The Tigers have been rolling lately though, now 7-3 in their last 10 games, and have been one of the hottest teams in the league since the trade deadline. The Tigers are going with Anderson in this one and he hasn't looked great this season. He is 4-4 with a 4.01 ERA and has mainly pitched out of the bullpen this year, so the Tigers will likely have more of a bullpen game here. Their bullpen has looked great lately though, not giving up many runs over the last week, and the offense has been hot too. The Guardians are going with Bibee in this one and he hasn't looked great this season. He is 4-11 with a 3.85 ERA and the team has had a lot of trouble with him this year. They have lost 3 of their last 4 games with him starting which has been a common theme for him and he did give up 3 earned runs in his last start too. This Guardians bullpen has also been giving up a ton of runs lately and it doesn't help that they have one of the worst offenses in MLB too. Look for the Tigers to continue rolling here as they have put themselves right back in the Wild Card race. The best way to place a bet here is on the Tigers to win this game. 

Guardians Tigers Prediction:  Our MLB Pick for Tuesday, August 11, 2026 (6:40 pm ET start time) is Tigers 7 Guardians 4.

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Cleveland Guardians: 243-212 (+24.8 units) on the moneyline in all games. 116-111 (+21.8 units) on the moneyline in road games. 90-106 (+12 units) on the moneyline as an underdog of +100 or higher. 29-18 UNDER when the total is 8 to 8.5.

Detroit Tigers: 239-219 (-6.4 units) on the moneyline in all games. 121-102 (-8.6 units) on the moneyline in home games. 138-102 (-8.7 units) on the moneyline as a favorite of -110 or higher. 36-18 UNDER when the total is 8 to 8.5.

Cleveland Guardians:  S. Cecconi (SP) Fifteen Day IL - Arm. S. Armstrong (RP) Sixty Day IL - Leg.

Detroit Tigers:  M. Vierling (CF) Ten Day IL - Adductor. K. Carpenter (RF) Ten Day IL - Heel. J. Flaherty (SP) Fifteen Day IL - Flexor. W. Vest (RP) Sixty Day IL - Elbow. B. Smith (RP) Sixty Day IL - Shoulder. W. Perez (RF) Sixty Day IL - Face. B. Hurter (RP) Sixty Day IL - Back. J. Verlander (SP) Sixty Day IL - Hip. B. Horn (RP) Sixty Day IL - Elbow. P. Meadows (CF) Sixty Day IL - Head/Arm. T. Sweeney (SS) Sixty Day IL - Shoulder. R. Olson (SP) Sixty Day IL - Shoulder.

“We're not thrilled. It's been around a couple weeks for us, and it's time to turn it around on Tuesday.” - Stephen Vogt after his team’s loss against the White Sox in their game on Sunday.

“There’s been a lot of noise around us and we keep stacking series wins. I obviously love the mindset of our team.” - A.J. Hinch after his team’s win against the Giants in their game on Sunday. 

Steven Kwan (L) CF

Chase DeLauter (L) RF

José Ramírez (S) 3B

Nathaniel Lowe (L) 1B

Jo Adell (R) LF

Travis Bazzana (L) DH

Brayan Rocchio (S) SS

Patrick Bailey (S) C

Angel Genao (S) 2B

Kevin McGonigle (L) SS

Gleyber Torres (R) 2B

Dillon Dingler (R) DH

Riley Greene (L) LF

Colt Keith (L) 3B

Spencer Torkelson (R) 1B

Max Clark (L) CF

Eduardo Valencia (R) C

Zach McKinstry (L) RF

Batting Average:  Angel Genao (.368)

Hits:  Chase DeLauter (105)

Home Runs:  Kyle Manzardo (13)

RBI:  Chase DeLauter (56)

Stolen Bases:  José Ramírez (29)

Wins:  Gavin Williams (11)

Saves:  Cade Smith (30)

ERA:  Colin Holderman (2.14)

Batting Average:  Eduardo Valencia (.390)

Hits:  Kevin McGonigle (125)

Home Runs:  Dillon Dingler (26)

RBI:  Dillon Dingler (80)

Stolen Bases:  Kevin McGonigle (11)

Wins:  Keider Montero (8)

Saves:  Kenley Jansen (13)

ERA:  Yilber Díaz (0.00)

Managers:

Cleveland Guardians: Stephen Vogt (3rd season)

Detroit Tigers: A.J. Hinch (6th season)