Cleveland Browns vs Tampa Bay Buccaneers Prediction, Preview and Odds - 09/20/2026

Game Time: 1:00 pm ET, Sunday, September 20, 2026

Venue:  Raymond James Stadium, Tampa, FL 

Where to Watch:  CBS

DraftKings:  Point Spread:  Browns +8.5, Buccaneers -8.5; Over/Under:  40.5 points

Bet365:  Point Spread:  Browns +8.5, Buccaneers -8.5; Over/Under:  40.5 points

BetMGM:  Point Spread:  Browns +8.5, Buccaneers -8.5; Over/Under:  41 points

Cleveland Browns:  0-1 (4th place, AFC North)

Tampa Bay Buccaneers:  0-1 (1st place, NFC South)

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Cleveland Browns:  lost their last game on the road against the Jacksonville Jaguars 34-10.

Tampa Bay Buccaneers:  lost their last game on the road against the Cincinnati Bengals 33-27.

The Browns are entering this game with a 0-1 record overall and they have a 0-0 record in their divisional games too. They are 0-0 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Jacksonville Jaguars 34-10. Deshaun Watson was the starting QB and he completed 16/22 passes for 205 passing yards, 1 touchdown, and 1 interception. Deshaun Watson led the team in rushing yards with 38. Denzel Boston led the receivers with 59 receiving yards on 2 receptions and 1 TD. Carson Schwesinger led the defense in that game with 10 solo tackles while Mason Graham led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

The Buccaneers are entering this game with a 0-1 record overall and they have a 0-0 record in their divisional games too. They are 0-0 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Cincinnati Bengals 33-27. Baker Mayfield was the starting QB and he completed 23/28 passes for 216 passing yards, 0 touchdowns, and 0 interceptions. Bucky Irving led the team in rushing yards with 45 and 1 TD. Emeka Egbuka led the receivers with 63 receiving yards on 5 receptions. Josiah Trotter led the defense in that game with 11 solo tackles while Josiah Trotter led the defense in sacks with 1. Josiah Trotter came away with the only interception for them in that one.

The current betting odds have the Buccaneers listed as an 8.5 point favorite in this game according to Draftkings Sportsbook. The Buccaneers haven't looked good in their games this season with their 0-1 record overall so far. They haven't played any home games yet and will be playing their home opener here. Meanwhile, the Browns have looked terrible in their games this season with their 0-1 record overall so far. They haven't been a good road team either with their 0-1 road record this year. The Browns are coming off a 34-10 loss to the Jaguars in week 1 and they looked like one of the worst teams in the NFL this season. They traded away their best player in the off-season and that defense looked a lot worse without Myles Garrett there. The offense had no rushing attack either and they don't have a real QB as long as Watson is still starting. Now they are on the road again and playing against a Buccaneers team that will be looking to bounce back at home in a big way. The Buccaneers were really sloppy in their season opener and the offense turned the ball over a ton, but they still only lost by 6 points in the end and managed to stay in the game even with a terrible start. The offense does have a lot of talent along with a solid QB to lead the charge, so they are going to clean things up in this game and shouldn't be as bad against this Cleveland defense. The Buccaneers are going to put up points in this one and the Browns aren't going to have a way back into the game once they fall behind as they aren't built to be chasing games. The best way to place a bet here is on the Buccaneers to cover the spread in this game. 

Browns Buccaneers Prediction:  Our NFL Pick for Sunday, September 20, 2026 (1:00 pm ET start time) is Buccaneers 27 Browns 7.

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Cleveland Browns: 8-3 ATS on the road against NFC South division opponents. 19-6 UNDER against NFC South division opponents. 76-47 UNDER in non-conference games. 13-7 UNDER as an underdog of 3.5 to 9.5 points.

Tampa Bay Buccaneers: 6-12 ATS in home games. 7-13 ATS as a favorite. 4-9 ATS as a home favorite. 4-7 ATS in non-conference games. 6-2 UNDER off a road loss. 

Cleveland Browns:  M. Collins (DL) Injured - Quad. T. Jenkins (OG) Out - Back. C. Schwesinger (LB) Injured - Shoulder. P. Brailsford (C) Questionable - Thumb.

Tampa Bay Buccaneers:  J. Skule (OT) Doubtful - Oblique. C. Rozeboom (LB) Questionable - Foot. S. Tucker (RB) Doubtful - Hamstring. J. McMillan (WR) Doubtful - Knee. E. Egbuka (WR) Injured - Toe. R. Bain Jr. (LB) Injured - Shoulder. B. Schrauth (OG) Injured - Knee.

“We did exactly what we wanted to start the game. We’re going to try to put them on their heels and then we turn it over. And then we couldn’t get a first down to get our defense off the field. That is a recipe to get run out of the arena.” - Todd Monken after his team’s loss against the Jags in their last game. 

“They upgraded the personnel a lot. They were running on some twists and being consistent. Relentless effort, you know. Like the last one, it’s (me) holding on to the ball too long, but those guys are running around the edge, so it’s relentless effort bringing it.” - Baker Mayfield after their loss against the Bengals in their last game. 

WR Boston, Denzel

WR Jeudy, Jerry

WR Concepcion, KC

TE Fannin Jr., Harold

QB Watson, Deshaun

RB Judkins, Quinshon

FB Burton, Michael

WR McMillan, Jalen

WR Egbuka, Emeka

WR Godwin Jr., Chris

TE Otton, Cade

QB Mayfield, Baker

RB Irving, Bucky

Passing: Deshaun Watson (205)

Rushing: Deshaun Watson (38)

Receiving: Denzel Boston (59)

Touchdowns: Denzel Boston (1)

Passing: Baker Mayfield (216)

Rushing: Bucky Irving (45)

Receiving: Emeka Egbuka (63)

Touchdowns: Bucky Irving (1)

Coaches:

Cleveland Browns: Todd Monken (1st season)

Tampa Bay Buccaneers: Todd Bowles (5th season)