Boston Red Sox vs Miami Marlins Prediction, Preview and Odds - 08/25/2026

Game Time: 6:40 pm ET, Tuesday, August 25, 2026

Venue:  LoanDepot Park, Miami, FL 

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Red Sox -161, Marlins +150; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Red Sox -160, Marlins +135; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Red Sox -160, Marlins +135; Over/Under:  7.5 runs

Boston Red Sox:  71-59 (3rd place, AL East)

Miami Marlins:  67-64 (3rd place, NL East)

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Boston Red Sox:  7-3 last 10

Miami Marlins:  5-5 last 10

The Red Sox are entering this series off a win and completed the sweep in their 3-game series against the San Francisco Giants 3-0 in their last series. They enter this game with a 71-59 record overall and have a road record of 37-27. This is the 2nd game of a 3-game series with the Marlins on Tuesday with the series opener still to be played on Monday. Their offense ranks 8th in the MLB with a .731 OPS. Ranger Suarez is their starting pitcher on Monday while Payton Tolle is making his start in this game on Tuesday. He is 8-6 with a 3.08 ERA this season. His team won 7 of their last 8 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 3 ER, 0 HR, and 2 BB with 6 SO on 6 hits through 5 IP against the Arizona Diamondbacks.

The Marlins are entering this series off a win and completed the sweep in their 3-game series against the Washington Nationals 3-0 in their last series. They enter this game with a 67-64 record overall and have a home record of 41-25. This is the 2nd game of a 3-game series with the Red Sox on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 9th in the MLB with a .728 OPS. Sandy Alcantara is their starting pitcher on Monday while Tyler Phillips is making his start in this game on Tuesday. He is 3-6 with a 3.67 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 2 walks with 3 strikeouts on 2 hits through 2 innings pitched against the Philadelphia Phillies.

The current betting odds have the Red Sox listed as a favorite in this game according to Draftkings Sportsbook. The Red Sox have looked really good in their games this season with their 71-59 record overall which has them right in the middle of the AL East. They have been a good road team too with their 38-28 road record this year. Meanwhile, the Marlins have looked good in their games this season with their 67-64 record overall which has them right in the middle of the NL East. They have looked great in their own ballpark too with their 41-25 home record this season. The Marlins have one of the best home records in the league this season and they just swept the Nationals there in their last series, but they still haven't looked great lately as they are 5-5 in their last 10 games. The Red Sox have been one of the hottest teams in MLB over the last 2 months, now back in a position to win the AL East, and they have been getting hot again lately with their 7-3 record in their last 10 games. Tolle is on the mound for the Red Sox in this one and he has looked great this season. He is 8-6 with a 3.08 ERA and the team has been having a ton of success with him lately. He did give up 3 earned runs in his last start, but that hasn't been a common theme for him and the team has still won 7 of their last 8 games with him starting. The bullpen has also been great for them lately and that is going to give them a big edge since the Marlins have been dealing with a lot of injuries, leaning heavily on their bullpen. Now they aren't going to have the best option starting in this game and the Red Sox will be able to take advantage of this pitching matchup. The best way to place a bet here is on the Red Sox to win this game. 

Red Sox Marlins Prediction:  Our MLB Pick for Tuesday, August 25, 2026 (6:40 pm ET start time) is Red Sox 4 Marlins 2.

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Boston Red Sox: 38-27 (+9.7 units) on the moneyline in road games. 37-23 (+12.4 units) on the moneyline when playing against a team with a winning record. 19-6 (+11.9 units) on the moneyline vs. a starting pitcher who lasts less than 5 innings per start. 33-25 OVER when playing against a team with a winning record.

Miami Marlins: 18-23 (-5.2 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 6-13 (-7.3 units) on the moneyline when playing against a good team (Win Pct. 54% to 62%). 7-18 (-7 units) on the moneyline vs. teams outscoring opp by 0.5 or more runs/game on the season. 10-5 OVER against AL East opponents.

Boston Red Sox:  J. Slaten (RP) Fifteen Day IL - Elbow. M. Yoshida (DH) Ten Day IL - Hamstring. G. Whitlock (RP) Fifteen Day IL - Elbow. I. Kiner-Falefa (2B) Sixty Day IL - Forearm. C. Mead (3B) Ten Day IL - Hand. Z. Kelly (RP) Sixty Day IL - Elbow. R. Anthony (LF) Sixty Day IL - Wrist. G. Crochet (SP) Sixty Day IL - Shoulder. T. Story (SS) Sixty Day IL - Abdomen. K. Crawford (SP) Sixty Day IL - Wrist. T. Casas (1B) Sixty Day IL - Knee. J. Oviedo (SP) Sixty Day IL - Elbow. T. Houck (SP) Sixty Day IL - Elbow.

Miami Marlins:  W. Kempner (RP) Sixty Day IL - Elbow. K. Stowers (1B) Ten Day IL - Hamstring. M. Meyer (SP) Fifteen Day IL - Neck. A. Bender (RP) Fifteen Day IL - Shin. A. Nardi (RP) Sixty Day IL - Ribs. R. Snelling (SP) Sixty Day IL - Elbow. A. Mazur (SP) Sixty Day IL - Elbow. R. Henriquez (RP) Sixty Day IL - Elbow.

“You can't say enough about it. You’re getting power swings on the left side, powerful swings on the right side. You're getting great defense. It's been enormous, the at-bats he's taken.” - Chad Tracy after his team’s win against the Giants in their game on Sunday. 

“This was certainly a very important series with where we are in the calendar, and being at home and having a chance to do that today.” - Clayton McCullough after his team’s win against the Nationals in their game on Sunday. 

Nick Sogard (S) SS

Ceddanne Rafaela (R) CF

Wilyer Abreu (L) RF

Willson Contreras (R) 1B

Adley Rutschman (S) C

Caleb Durbin (R) 3B

Jarren Duran (L) LF

Mickey Gasper (S) DH

Anthony Seigler (S) 2B

Otto Lopez (R) SS

Heriberto Hernández (R) LF

Kyle Stowers (L) 1B

Agustín Ramírez (R) DH

Xavier Edwards (S) 2B

Jakob Marsee (L) CF

Javier Sanoja (R) 3B

Esteury Ruiz (R) RF

Joe Mack (L) C

Batting Average:  Jahmai Jones (.520)

Hits:  Ceddanne Rafaela (143)

Home Runs:  Willson Contreras (26)

RBI:  Willson Contreras (78)

Stolen Bases:  Jarren Duran (18)

Wins:  Sonny Gray (16)

Saves:  Aroldis Chapman (29)

ERA:  Erik Miller (0.00)

Batting Average:  Deyvison De Los Santos (.333)

Hits:  Otto Lopez (155)

Home Runs:  Heriberto Hernandez (19)

RBI:  Liam Hicks (62)

Stolen Bases:  Esteury Ruiz (29)

Wins:  Sandy Alcantara (13)

Saves:  Pete Fairbanks (18)

ERA:  Jack Ralston (0.00)

Managers:

Boston Red Sox: Chad Tracy (Interim)

Miami Marlins: Clayton McCullough (2nd season)