Atlanta Braves vs Milwaukee Brewers Prediction, Preview and Odds - 08/22/2026

Game Time: 2:10 pm ET, Saturday, August 22, 2026

Venue:  American Family Field, Milwaukee, WI

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Braves +139, Brewers -168; Over/Under:  8 runs

Bet365:  Moneyline odds:  Braves +140, Brewers -170; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Braves +140, Brewers -170; Over/Under:  8 runs

Atlanta Braves:  75-53 (1st place, NL East)

Milwaukee Brewers:  79-49 (1st place, NL Central)

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Atlanta Braves:  4-6 last 10

Milwaukee Brewers:  5-5 last 10

The Braves are entering this series off a win and won their 1-off game against the Chicago White Sox on Thursday. They enter this game with a 75-53 record overall and have a road record of 33-30. This is the 2nd game of a 3-game series with the Brewers on Saturday with the series opener still to be played on Friday. Their offense ranks 14th in the MLB with a .723 OPS. Chris Sale is their starting pitcher on Friday while Martín Pérez is making his start in this game on Saturday. He is 8-7 with a 3.15 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 4 ER, 0 HR, and 2 BB with 3 SO on 9 hits through 5 IP against the Minnesota Twins.

The Brewers are entering this series off a win and won their 3-game series against the Seattle Mariners 2-1 in their last series. They enter this game with a 79-49 record overall and have a home record of 43-23. This is the 2nd game of a 3-game series with the Braves on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 7th in the MLB with a .734 OPS. Jacob Misiorowski is their starting pitcher on Friday while Logan Henderson is making his start in this game on Saturday. He is 7-2 with a 2.70 ERA this season. His team won 9 of their last 10 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 1 homer, and 1 walk with 6 strikeouts on 3 hits through 7 innings pitched against the Los Angeles Dodgers.

The current betting odds have the Brewers listed as a favorite in this game according to Draftkings Sportsbook. The Brewers have looked great in their games this season with their 79-49 record overall which has them right at the top of the NL Central with the best record in MLB. They have looked great in their own ballpark too with their 43-23 home record this season. Meanwhile, the Braves have looked great in their games this season with their 75-53 record overall which has them right at the top of the NL East with one of the best records in MLB. They have been a good road team too with their 33-30 road record this year. The Braves just won a single game against the White Sox on Thursday which was a make-up game, but they haven't looked that good lately. They are 4-6 in their last 10 games and just got swept by the Twins in their last series. The Brewers haven't looked great lately either, now 5-5 in their last 10 games, but they just won their last series over the Mariners and they are going to have the better pitching matchup here. The Brewers are going with Henderson in this one and he has looked great this season. He is 7-2 with a 2.70 ERA and the team has been having a ton of success with him lately. He is coming off another great start giving up 1 earned run which has been a common theme for him all season and the team has won 9 of their last 10 games with him starting too. The Braves are going with Perez in this one and he has looked good this season. He is 8-7 with a 3.15 ERA and his team has been having success with him lately too. They have won 3 of their last 4 games with him starting, but he did give up 4 earned runs in his last start and he has had some starts in which he looked really shaky. The Braves haven't been putting up a ton of runs lately either while the Brewers offense has been rolling, so look for the Brewers to have the edge at home here where they have looked so much better this season. The best way to place a bet here is on the Brewers to win this game. 

Braves Brewers Prediction:  Our MLB Pick for Saturday, August 22, 2026 (2:10 pm ET start time) is Brewers 4 Braves 2.

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Atlanta Braves: 41-41 (-10.9 units) on the moneyline against NL Central opponents. 240-214 (-43 units) on the moneyline in all games. 113-114 (-21.8 units) on the moneyline in road games. 13-7 UNDER as a road underdog of +100 to +150.

Milwaukee Brewers: 273-192 (+51.6 units) on the moneyline in all games. 145-90 (+23.9 units) on the moneyline in home games. 174-105 (+22.8 units) on the moneyline as a favorite of -110 or higher. 23-10 UNDER against left-handed starters.

Atlanta Braves:  R. Lopez (SP) Fifteen Day IL - Knee. R. Suarez (RP) Fifteen Day IL - Elbow. S. Strider (SP) Sixty Day IL - Elbow. J. Wentz (RP) Sixty Day IL - Knee. J. Jimenez (RP) Sixty Day IL - Knee. S. Schwellenbach (SP) Sixty Day IL - Elbow.

Milwaukee Brewers:  A. Uribe (RP) Fifteen Day IL - Forearm. S. Frelick (RF) Ten Day IL - Shoulder. J. Romero (RP) Fifteen Day IL - Appendix. R. Zastryzny (RP) Sixty Day IL - Shoulder. B. Woodruff (SP) Sixty Day IL - Shoulder. J. Kuhnel (RP) Fifteen Day IL - Shoulder. Q. Priester (SP) Sixty Day IL - Wrist. B. Fitzpatrick (RP) Sixty Day IL - Elbow. A. Zerpa (RP) Sixty Day IL - Forearm.

“You got to keep playing. You got to turn the page and take on the next challenge, and I think our guys are really good at that. We got a good team, and we’re in first place. It’s a good group.” - Walt Weiss after his team’s win against the White Sox in their game on Thursday. 

“I was kind of hot. I was a little too emotional right there. You can’t walk guys.” - Pat Murphy after his team’s win against the Mariners in their game on Thursday.

Ronald Acuña Jr. (R) RF

Drake Baldwin (L) DH

Matt Olson (L) 1B

Ozzie Albies (S) 2B

Lane Thomas (R) LF

Michael Harris II (L) CF

Mauricio Dubón (R) SS

Austin Riley (R) 3B

Sean Murphy (R) C

Brice Turang (L) 2B

Jackson Chourio (R) LF

Jake Bauers (L) 1B

Gary Sánchez (R) C

Christian Yelich (L) DH

Joey Ortiz (R) SS

Garrett Mitchell (L) CF

David Hamilton (L) 3B

Luis Lara (S) RF

Batting Average:  Jair Camargo (.500)

Hits:  Michael Harris (135)

Home Runs:  Matt Olson (36)

RBI:  Matt Olson (77)

Stolen Bases:  Ronald Acuña (16)

Wins:  Chris Sale (12)

Saves:  Raisel Iglesias (26)

ERA:  Hunter Stratton (0.00)

Batting Average:  Jihwan Bae (.500)

Hits:  Brice Turang (121)

Home Runs:  Jake Bauers (22)

RBI:  Brice Turang (75)

Stolen Bases:  David Hamilton (24)

Wins:  Aaron Ashby (13)

Saves:  Trevor Megill (23)

ERA:  Easton McGee (0.00)

Managers:

Atlanta Braves: Walt Weiss (1st season)

Milwaukee Brewers: Pat Murphy (3rd season)