Arizona Diamondbacks vs San Diego Padres Prediction, Preview and Odds - 07/07/2026

Game Time: 9:40 pm ET, Tuesday, July 7, 2026

Venue:  Petco Park, San Diego, CA

Where to Watch:  ESPN Unlimited, MLB TV

DraftKings:  Moneyline odds:  Diamondbacks +109, Padres -131; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Diamondbacks +105, Padres -125; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Diamondbacks +105, Padres -125; Over/Under:  8.5 runs

Arizona Diamondbacks:  44-45 (2nd place, NL West)

San Diego Padres:  44-45 (3rd place, NL West)

Do not miss out on our expert handicapper analysis! Brian Bitler is on a HOT STREAK in MLB on a 9-4 MLB RUN for +$5,430 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Arizona Diamondbacks:  4-6 last 10

San Diego Padres:  2-8 last 10

The Diamondbacks are entering this series off a loss and lost their 3-game series against the Milwaukee Brewers 2-1 in their last series. They enter this game with a 44-45 record overall and have a road record of 17-25. This is the 2nd game of a 4-game series with the Padres on Tuesday with the series opener still to be played on Monday. Their offense ranks 26th in the MLB with a .689 OPS. Brandon Pfaadt is their starting pitcher on Monday while Zac Gallen is making his start in this game on Tuesday. He is 3-8 with a 6.36 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 6 ER, 2 HR, and 1 BB with 4 SO on 7 hits through 5.2 IP against the San Francisco Giants.

The Padres are entering this series off a win and lost their 4-game series against the Los Angeles Dodgers 3-1 in their last series. They enter this game with a 44-45 record overall and have a home record of 23-21. This is the 2nd game of a 4-game series with the Diamondbacks on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 30th in the MLB with a .674 OPS. Walker Buehler is their starting pitcher on Monday while Germán Márquez is making his start in this game on Tuesday. He is 3-2 with a 5.79 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 0 homers, and 3 walks with 1 strikeouts on 2 hits through 3 innings pitched against the Los Angeles Dodgers.

The current betting odds have the Padres listed as a favorite in this game according to Draftkings Sportsbook. The Padres haven't looked good in their games this season with their 44-45 record overall, but that record has them right near the top of the NL West. They have looked a lot better in their own ballpark though with their 23-21 home record this season. Meanwhile, the Diamondbacks haven't looked great in their games this season with their 44-45 record overall which has them right in the middle of the NL West. They have been a bad road team too with their 17-25 road record this year. Neither team has looked great lately as the Padres are 2-8 in their last 10 games and the Diamondbacks are 4-6. Neither offense has been that good this season either, but the Padres are going to have the better pitching matchup in this one and they can take advantage of that. The Diamondbacks are going with Gallen in this one too and he has looked terrible this season. He is 3-8 with a 6.36 ERA and he has been giving up a ton of runs all year. He is coming off another terrible start in which he gave up 6 earned runs and that has been a common theme for him. The team has also lost 3 games in a row now with him starting and he has been racking up losses for them all year. The Padres don't have a great offense, but neither do the Diamondbacks, and this is definitely a pitching matchup that they can take advantage of at home. The best way to place a bet here is on the Padres to win this game. 

Diamondbacks Padres Prediction:  Our MLB Pick for Tuesday, July 7, 2026 (9:40 pm ET start time) is Padres 6 Diamondbacks 2.

Don't miss our champion handicappers free picks, best bets, and expert baseball picks today.  And if you enjoyed this Arizona Diamondbacks San Diego Padres prediction, be sure to drop by every day for our daily MLB projections and previews.

Arizona Diamondbacks: 212-201 (-3.7 units) on the moneyline in all games. 149-140 (-3.8 units) on the moneyline against right-handed starters. 97-83 (-8.4 units) on the moneyline when playing against a team with a losing record. 25-18 UNDER vs. an NL team with a team batting average of .255 or worse.

San Diego Padres: 233-191 (+21.5 units) on the moneyline in all games. 123-87 (+8.9 units) on the moneyline in home games. 169-137 (+16.2 units) on the moneyline against right-handed starters. 16-10 UNDER vs. a team with a poor bullpen whose ERA is 4.20 or worse.

Arizona Diamondbacks:  M. Soroka (SP) Fifteen Day IL - Lower-Body. J. Lawlar (LF) Ten Day IL - Hamstring. R. Nelson (SP) Sixty Day IL - Elbow. J. McCann (C) Ten Day IL - Quad. B. Walston (SP) Sixty Day IL - Elbow. C. Mena (SP) Sixty Day IL - Shoulder. A. Puk (RP) Sixty Day IL - Elbow. C. Burnes (SP) Sixty Day IL - Elbow. J. Martinez (RP) Sixty Day IL - Elbow. A. Saalfrank (RP) Sixty Day IL - Shoulder.

San Diego Padres:  F. Fermin (C) Ten Day IL - Head. R. Vasquez (SP) Fifteen Day IL - Ankle. J. Adam (RP) Fifteen Day IL - Shoulder. D. Morgan (RP) Fifteen Day IL - Knee. L. Giolito (SP) Fifteen Day IL - Elbow. J. Estrada (RP) Fifteen Day IL - Knee. R. Laureano (LF) Sixty Day IL - Hip. N. Pivetta (SP) Sixty Day IL - Elbow. M. Waldron (SP) Fifteen Day IL - Arm. B. Hoeing (RP) Sixty Day IL - Elbow. J. Musgrove (SP) Sixty Day IL - Elbow.

"Nobody wants to go through what we went through last year. I didn't like the way that it felt last year, and we had to say goodbye to a lot of really important players. It was a tough month, and I'll remind the guys of that. So, let's grow and learn and not let it happen again, and go on to win some baseball games, because that's what we have to do." - Torey Lovullo after his team’s loss against the Brewers in their game on Sunday. 

“You just have to win after the losing streak. Whenever that win happens, it’s a big win. And it allows us to take a breath, and then get back after it. Going back home is also a helpful thing -- and being able to start that homestand with a good feeling is a positive for our team.” - Craig Stammen after his team’s win against the LA Dodgers in their game on Sunday. 

Ketel Marte (S) DH

Geraldo Perdomo (S) SS

Corbin Carroll (L) RF

Gabriel Moreno (R) C

Lourdes Gurriel Jr. (R) LF

Ildemaro Vargas (S) 2B

Tim Tawa (R) 3B

Pavin Smith (L) 1B

Tommy Troy (R) CF

Fernando Tatis Jr. (R) RF

Jake Cronenworth (L) DH

Manny Machado (R) 3B

Gavin Sheets (L) LF

Ty France (R) 1B

Jackson Merrill (L) CF

Xander Bogaerts (R) SS

Sung-Mun Song (L) 2B

Luis Campusano (R) C

Batting Average:  Jordan Lawlar (.316)

Hits:  Ketel Marte (91)

Home Runs:  Ketel Marte (17)

RBI:  Ketel Marte (54)

Stolen Bases:  Geraldo Perdomo (13)

Wins:  Michael Soroka (8)

Saves:  Paul Sewald (20)

ERA:  Taylor Clarke (2.06)

Batting Average:  Samad Taylor (.329)

Hits:  Fernando Tatis (98)

Home Runs:  Manny Machado (18)

RBI:  Manny Machado (51)

Stolen Bases:  Fernando Tatis (21)

Wins:  Randy Vásquez (6)

Saves:  Mason Miller (22)

ERA:  Mason Miller (0.98)

Managers:

Arizona Diamondbacks: Torey Lovullo (10th season)

San Diego Padres: Craig Stammen (1st season)