by Rod Pearson
Tuesday, Oct 27, 2026
Game Time: 1:00 pm ET, Sunday, November 1, 2026
Venue: AT&T Stadium, Arlington, TX
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Cardinals +6.5, Cowboys -6.5; Over/Under: 54.5 points
Bet365: Point Spread: Cardinals +6.5, Cowboys -6.5; Over/Under: 54.5 points
BetMGM: Point Spread: Cardinals +6.5, Cowboys -6.5; Over/Under: 54.5 points
Season Record
Arizona Cardinals: 2-5 (4th place, NFC West)
Dallas Cowboys: 3-4 (2nd place, NFC East)
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Recent Form
Arizona Cardinals: lost their last game at home against the Denver Broncos 30-16.
Dallas Cowboys: won their last game on the road against the Philadelphia Eagles 38-21.
Arizona Cardinals vs Dallas Cowboys Preview and Analysis
The Cardinals are entering this game with a 2-5 record overall and they have a 1-2 record in their divisional games too. They are 0-3 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Denver Broncos 30-16. Jacoby Brissett was the starting QB and he completed 27/48 passes for 272 passing yards, 1 touchdown, and 0 interceptions. Zonovan Knight led the team in rushing yards with 48. Trey McBride led the receivers with 111 receiving yards on 10 receptions and 1 TD. Jack Gibbens led the defense in that game with 7 solo tackles while Darius Robinson led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
The Cowboys are entering this game with a 3-4 record overall and they have a 2-1 record in their divisional games too. They are 1-1 in their home games, 2-2 in their road games, and they are also 0-1 in their neutral site games this season, but they will be at home for this game. They won their last game against the Philadelphia Eagles 38-21. Dak Prescott was the starting QB and he completed 15/27 passes for 212 passing yards, 3 touchdowns, and 0 interceptions. Javonte Williams led the team in rushing yards with 155 and 1 TD. CeeDee Lamb led the receivers with 74 receiving yards on 5 receptions and 2 TDs. DeMarvion Overshown and Shemar James each led the defense in that game with 6 solo tackles while Quinnen Williams and Donovan Ezeiruaku each led the defense in sacks with 1. DeMarvion Overshown came away with the only interception for them in that one.
Cardinals vs Cowboys Prediction
The current betting odds have the Cowboys listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The Cowboys haven't looked good in their games this season with their 3-4 record overall, but that record has them right near the top of the NFC East. They haven't looked great on their home field with their 1-1 home record this season. Meanwhile, the Cardinals haven't looked good in their games this season with their 2-5 record overall which has them right at the bottom of the NFC West. They haven't been a great road team either with their 2-2 road record this year. The Cardinals have looked better in their road games this year with their only 2 wins this season both coming on the road, but they do not have a good team this season and will end up as one of the worst in the NFL. They are coming off a 30-16 loss to the Broncos in their last one and that defense has been giving up a ton of points all season. They have some talent on offense, but they don't have a great QB to lead this offense and have been really up and down all year. The Cowboys have had a lot of trouble this season too, but they are in a really bad division that they still have a great chance to win, so they are going to be motivated to get back to .500 here. They are coming off a feel good win over the Eagles in their last one, winning on the road 38-21, and this is another team that they should be able to pick up a feel good win against and start building some momentum. The Cowboys have one of the best offenses in the NFL with the talent they have and even though their defense hasn't looked good all year, the Cardinals don't have the talent to keep up with this Cowboys offense for 4 quarters. The best way to place a bet here is on the Cowboys to cover the spread in this game.
Cardinals Cowboys Prediction: Our NFL Pick for Sunday, November 1, 2026 (1:00 pm ET start time) is Cowboys 45 Cardinals 24.
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NFL Betting Trends
Arizona Cardinals: 8-3 ATS as a road underdog of 7 points or less. 31-19 ATS against NFC East division opponents. 25-19 ATS versus poor rushing defenses - allowing 130 rushing yards/game or more. 10-5 OVER after allowing 30 points or more last game. 8-3 OVER vs. good offensive teams - scoring 24 or more points/game.
Dallas Cowboys: 5-10 ATS as a favorite. 3-11 ATS in all games where the total is greater than or equal to 49.5. 1-5 ATS when playing against a bad team (Win Pct. 25% to 40%). 8-3 OVER as a favorite of 3.5 to 9.5 points. 10-4 OVER in a home game where the total is greater than or equal to 45.5.
Key Injuries
Arizona Cardinals: B. Baker (S) Injured - Rest. I. Seumalo (OG) Injured - Rest. E. Wilkinson (OG) Injured - Knee. M. Wilson Sr. (LB) Injured - Rest. J. Sweat (LB) Injured - Rest. Z. Collins (LB) Injured - Illness. A. Wingard (S) Injured - Knee. J. Gaines II (OG) Injured - Ankle. M. Wilson (WR) Injured - Ribs. T. Allgeier (RB) Injured - Toe. K. Clark (CB) Injured - Illness. M. Melton (CB) Injured - Knee. W. Nolen III (DL) Injured - Ankle. J. Love (RB) Injured - Ankle. C. Beck (QB) Injured - Back.
Dallas Cowboys: Q. Williams (DL) Injured - Hamstring. P. Locke (S) Injured - Foot. K. Turpin (WR) Injured - Ribs. D. Winters (LB) Injured - Calf. G. Pickens (WR) Injured - Shoulder. M. Liufau (LB) Injured - Forearm. C. Downs (CB) Injured - Ankle. D. Shelton (OT) Injured - Hamstring.
Notable Quotes
“We've got to play better. We had too many penalties, we had opportunities to make plays and we didn't. When we get to the point where we're gonna flip this thing, we've got to make those plays. This is a collective deal in terms of coaching and playing.” - Mike LaFleur after his team’s loss against the Broncos in their last game.
“Javonte, man, the power, the acceleration, it was there tonight. He looked great.” - Brian Schottenheimer after his team’s win against the Eagles in their last game.
Starting Lineups
Arizona Cardinals
WR Fehoko, Simi
WR Wilson, Michael
WR Bourne, Kendrick
TE McBride, Trey
QB Brissett, Jacoby
RB Allgeier, Tyler
Dallas Cowboys
WR Pickens, George
WR Lamb, CeeDee
WR Flournoy, Ryan
TE Ferguson, Jake
QB Prescott, Dak
RB Williams, Javonte
FB Luepke, Hunter
Statistical Leaders
Arizona Cardinals
Passing: Jacoby Brissett (1,600)
Rushing: Jeremiyah Love (245)
Receiving: Trey McBride (472)
Touchdowns: Trey McBride (4)
Dallas Cowboys
Passing: Dak Prescott (1,851)
Rushing: Javonte Williams (472)
Receiving: CeeDee Lamb (651)
Touchdowns: Javonte Williams (9)
Coaches:
Arizona Cardinals: Mike LaFleur (1st season)
Dallas Cowboys: Brian Schottenheimer (2nd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
